January 18, 2016



52. Wang Z. Y., Pergande M. R., Ragsdale C. W., Cologna S. M. Steroid hormones of the octopus self-destruct system. Curr Biol, May 5, 2022. doi: 10.1016/j.cub.2022.04.043

51. Park H. S., Chugh R. M., Pergande M. R., Cetin E., Siblini H., Esfandyari S., Cologna S. M., Al-Hendy A. Non-Cytokine Protein Profile of the Mesenchymal Stem Cell Secretome That Regulates the Androgen Production Pathway. Int J Mol Sci, Apr 22, 2022. doi: 10.3390/ijms23094633

50. Pergande M. R., Kang C., George D., Sutter P. A., Crocker S. J., Cologna S. M., and Givogri M. I. Lipidomic analysis identifies age-disease-related changes and potential new biomarkers in brain-derived extracellular vesicles from metachromatic leukodystrophy mice. Lipids Health Dis, Mar 27, 2022. doi: 10.1186/s12944-022-01644-8

49. Li W. and Cologna S. M. Mass spectrometry-based proteomics in neurodegenerative lysosomal storage disorders. Mol Omics, Mar 28, 2022. doi: 10.1039/d2mo00004k

48. Reiter C. R., Rebiai R., Kwak A., Marshall J., Wozniak D., Scesa G., Nguyen D., Rue E., Pathmasiri K. C., Pijewski R., van Breemen R., Cologna S. M., Crocker S. J., Givogri M. I., Bongarzone E. R. The Pathogenic Sphingolipid Psychosine is Secreted in Extracellular Vesicles in the Brain of a Mouse Model of Krabbe Disease. ASN Neuro, Mar 18, 2022. doi: 10.1177/17590914221087817

47. Salvi A., Young A. N., Huntsman A. C., Pergande M. R., Korkmaz M. A., Rathnayake R. A. C., Mize B. K., Kinghorn A. D., Zhang X., Ratia K., Schirle M., Thomas J. R., Brittain S. M., Shelton C., Aldrich L. N., Cologna S. M., Fuchs J. R., Burdette J. E. PHY34 inhibits autophagy through V-ATPase V0A2 subunit inhibition and CAS/CSE1L nuclear cargo trafficking in high grade serous ovarian cancer. Cell Death Dis, Jan 10, 2022. doi: 10.1038/s41419-021-04495-w


46. Pathmasiri K. C., Nguyen T. T. A., Khamidova N., Cologna S. M. Chapter Ten - Mass spectrometry-based lipid analysis and imaging. In: Model, M. A and Levitan I. (eds) Current Topics in Membranes. Academic Press, Vol 88. Nov 9, 2021. doi: 10.1016/bs.ctm.2021.10.005

45. Pergande M. R., Amoroso V. G., Nguyen T. T. A., Li W., Vice E., Park T. J., and Cologna S. M. PPARα and PPARγ Signaling Is Enhanced in the Brain of the Naked Mole-Rat, a Mammal that Shows Intrinsic Neuroprotection from Oxygen DeprivationJ Proteome Res, Aug 5, 2021. doi: 10.1021/acs.jproteome.1c00131

44. Son K. N., Lee H., Shah D., Kalmodia S., Miller R. C., Ali M., Balasubramaniam A., Cologna S. M., Kong H., Shukla D., and Aakalu V. K. Histatin-1 is an endogenous ligand of the sigma-2 receptorFEBS J, Jun 11, 2021. doi: 10.1111/febs.16108

43. Abbasi D. A., Nguyen T. T. A, A. Hall D. A., Robertson-Dick E., Berry-Kravis E., and Cologna S. M. Characterization of the Cerebrospinal Fluid Proteome in Patients with Fragile X-Associated Tremor/Ataxia SyndromeCerebellum, Mar 27, 2021. doi: 10.1007/s12311-021-01262-7

42. Angelini R., Yutuc E., Wyatt M. F., Newton J., Yusuf F. A., Griffiths L., Cooze B. J., El Assad D., Frache G., Rao W., Allen L. B., Korade Z., Nguyen T. T. A., Rathnayake R. A. C., Cologna S. M., Howell O. W., Clench M. R., Wang Y., Griffiths W. J. Visualizing Cholesterol in the Brain by On-Tissue Derivatization and Quantitative Mass Spectrometry ImagingAnal Chem, Mar 9, 2021. doi: 10.1021/acs.analchem.0c05399

41. Rebiai R., Givogri M. I., Gowrishankar S., Cologna S. M., Alford S. T., Bongarzone E. R. Synaptic Function and Dysfunction in Lysosomal Storage DiseasesFront Cell Neurosci, Mar 4, 2021. doi: 10.3389/fncel.2021.619777

40. Heller G. J., Marshall M. S., Issa Y., Marshall J. N., Nguyen D., Rue E., Pathmasiri K. C., Domowicz M. S., van Breemen R. B., Tai L. M., Cologna S. M., Crocker S. J., Givogri M. I, Sands M. S., Bongarzone E. R. Waning efficacy in a long-term AAV-mediated gene therapy study in the murine model of Krabbe diseaseMol Ther, Jan 26, 2021. doi: 10.1016/j.ymthe.2021.01.026


39. Frankel D., Davies M., Bhushan B., Kulaberoglu Y., Urriola-Munoz P., Bertrand-Michel J., Pergande M. R., Smith A. A., Preet S., Park T. J., Vendruscolo M., Rankin K. S., Cologna S. M., Kumita J. R., Cenac N., St John Smith E. Cholesterol-rich naked mole-rat brain lipid membranes are susceptible to amyloid beta-induced damage in vitroAging, Nov 4, 2020. doi: 10.18632/aging.202138

38. Gowrishankar S., Cologna S. M, Givogri M. I., Bongarzone E. R. Deregulation of signalling in genetic conditions affecting the lysosomal metabolism of cholesterol and galactosyl-sphingolipidsNeurobiol Dis, Oct 17, 2020. doi: 10.1016/j.nbd.2020.105142

37. Olson M. T., Yergey A. L., Mukherjee K., Pergande M. R., Bane S. L., Cologna S. M., Sackett D. L. Taurine is covalently incorporated into alpha tubulinJ Proteome Res, May 13, 2020. doi: 10.1021/acs.jproteome.0c00147

36. Pathmasiri K. C., Pergande M. R., Tobias F., Rebiai R., Rosenhouse-Dantsker A., Bongarzone E. R., Cologna S. M. Mass spectrometry imaging and LC–MS reveal decreased cerebellar phosphoinositides in Niemann–Pick type C1–null miceJ Lipid Res, May 5, 2020. doi: 10.1194/jlr.RA119000606

35. Tobin M. K., Stephen T. K. L., Lopez K. L., Pergande M. R., Bartholomew A. M., Cologna S. M., Lazarov O. Activated Mesenchymal Stem Cells Induce Recovery Following Stroke Via Regulation of Inflammation and Oligodendrogenesis. J Am Heart Assoc, Apr 7, 2020. doi: 10.1161/JAHA.119.013583

34. Teclemariam E. T., Pergande M. R., Cologna S. M. Considerations for mass spectrometry-based multi-omic analysis of clinical samples. Expert Rev Proteomics, Feb 07, 2020. doi: 10.1080/14789450.2020.1724540


33. Cologna S. M. A calcium message for Niemann-Pick type C. J Cell Biol, Nov 14, 2019. doi: 10.1083/jcb.201911021

32. Pergande M. R., Serna-Perez F., Mohsin S. B., Hanek J., Cologna S. M. Lipidomic Analysis Reveals Altered Fatty Acid Metabolism in the Liver of the Symptomatic Niemann-Pick, Type C1 Mouse Model. Proteomics, Aug 29, 2019. doi: 10.1002/pmic.201800285

31. Hardy L. R., Pergande M. R., Esparza K., Heath K. N., Önyüksel H., Cologna S. M., Burdette J. E. Proteomic analysis reveals a role for PAX8 in peritoneal colonization of high grade serous ovarian cancer that can be targeted with micelle encapsulated thiostrepton. Oncogene, Jul 11, 2019. doi:10.1038/s41388-019-0842-2

30. Tobias F., Pathmasiri K. C., Cologna S. M. Mass spectrometry imaging reveals ganglioside and ceramide localization patterns during cerebellar degeneration in the Npc1-/- mouse model. Anal Bioanal Chem, Jun 29, 2019. doi: 10.1007/s00216-019-01989-7

29. Pergande M. R., Zarate E., Haney-Ball C., Davidson C. D., Scesa G., Givogri M. I., Bongarzone E. R., Cologna S. M. Standard-flow LC and thermal focusing ESI elucidates altered liver proteins in late stage Niemann-Pick, type C1 disease. Bioanalysis, Jun 28, 2019. doi: 10.4155/bio-2018-0232

28. Nguyen T. T. A., Li W., Park T. J., Gong L. W., Cologna S. M. Investigating Phosphorylation Patterns of the Ion Channel TRPM7 Using Multiple Extraction and Enrichment Techniques Reveals New Phosphosites. J Am Soc Mass Spectrom, May 28, 2019. doi: 10.1007/s13361-019-02223-5

27. Cologna S. M., Rosenhouse-Dantsker A. Insights into the Molecular Mechanisms of Cholesterol Binding to the NPC1 and NPC2 Proteins. In: Rosenhouse-Dantsker A., Bukiya A. (eds) Direct Mechanisms in Cholesterol Modulation of Protein Function. Adv Exp Med Biol, Vol 1135. Springer, Cham. May 17, 2019. doi: 10.1007/978-3-030-14265-0_8

26. Mazinani, S. A., Noaman N., Pergande, M. R, Cologna, S. M., Coorssen, J. and Yan, H. Exposure to microwave irradiation at constant culture temperature slows the growth of Escherichia coli DE3 cells, leading to modified proteomic profiles. RSC Adv., Apr 7, 2019. DOI: 10.1039/c9ra00617f

25. Jiang Z. J., Delaney T. L., Zanin M. P., Haberberger R. V., Pitson S. M., Huang J., Alford S., Cologna S. M., Keating D. J., Gong L. W. Extracellular and intracellular sphingosine-1-phosphate distinctly regulates exocytosis in chromaffin cells. J Neurochem, Apr 09, 2019. doi: 10.1111/jnc.14703

24. Kurgan N., Noaman N., Pergande M. R., Cologna S. M., Coorssen J. R., Klentrou P. Changes to the Human Serum Proteome in Response to High Intensity Interval Exercise: A Sequential Top-Down Proteomic Analysis. Front Physiol, Apr 2, 2019. doi: 10.3389/fphys.2019.00362

23. Pergande M. R., Nguyen T. T. A., Haney-Ball C., Davidson C. D., Cologna S. M. Quantitative, label-free proteomics in the symptomatic Niemann-Pick, type C1 mouse model using standard flow liquid chromatography and thermal focusing electrospray ionization. Proteomics, Mar 19, 2019. doi: 10.1002/pmic.201800432

22. Pergande M. R., Cougnoux A., Rathnayake R. A. C., Porter F. D., Cologna S. M. Differential Proteomics Reveals miR-155 as a Novel Indicator of Liver and Spleen Pathology in the Symptomatic Niemann-Pick Disease, Type C1 Mouse Model. Molecules, Mar 12, 2019. doi: 10.3390/molecules24050994

21. Cologna, S. M. Mass Spectrometry Imaging of Cholesterol. In: Cholesterol Modulation of Protein Function, Rosenhouse-Dantsker A., Bukiya A. (eds). Advances in Experimental Medicine and Biology, vol 1115. Jan 2019. doi: 10.1007/978-3-030-04278-3_7

20. Gale P. J., Cologna, S. M. Alfred L. Yergey III (September 17, 1941–May 27, 2018). J Am Soc Mass Spectrom. Jan 14, 2019, 30: 557. doi: 10.1007/s13361-018-2097-5


19. Klein C., Cologna S. M., Kurulugama R. T., Blank P. S., Darland E., Mordehai A., Backlund P. S., Yergey A. L.
Cyclodextrin and malto-dextrose collision cross sections determined in a drift tube ion mobility mass spectrometer using nitrogen bath gas. Analyst, Aug 20, 2018. doi: 10.1039/c8an00646f

18. Tobias, F.; Olson, M. T.; Cologna, S. M. Mass Spectrometry Imaging of Lipids: Generation of Untargeted Consensus Spectra Reveals Spatial Distributions in Niemann-Pick Disease, Type C1. J Lipid Res, 2018. doi: 10.1194/jlr.D086090


17. Yergey, A. L.; Blank, P. S.; Cologna, S. M.; Backlund, P. S.; Porter, F. D.; Darling, A. J., Characterization of hydroxypropyl-beta-cyclodextrins used in the treatment of Niemann-Pick Disease type C1. PLOS ONE 2017, 12 (4), e0175478.

16. Pergande, R. M.; Cologna, M. S., Isoelectric Point Separations of Peptides and Proteins. Proteomes 2017, 5 (1). doi:10.3390/proteomes5010004


15. May-Simera, Helen L.; Gumerson, Jessica D.; Gao, C.; Campos, M.; Cologna, Stephanie M.; Beyer, T.; Boldt, K.; Kaya, Koray D.; Patel, N.; Kretschmer, F.; Kelley, Matthew W.; Petralia, Ronald S.; Davey, Megan G.; Li, T., Loss of MACF1 Abolishes Ciliogenesis and Disrupts Apicobasal Polarity Establishment in the Retina. Cell Reports 2016, 17 (5), 1399-1413. doi: 10.1016/j.celrep.2016.09.089

14. Epstein, J. A.; Blank, P. S.; Searle, B. C.; Catlin, A. D.; Cologna, S. M.; Olson, M. T.; Backlund, P. S.; Coorssen, J. R.; Yergey, A. L., ProteinProcessor: A probabilistic analysis using mass accuracy and the MS spectrum. PROTEOMICS 2016, 16 (18), 2480-2490. doi: 10.1002/pmic.201600137

13. Cologna, S. M.; Shieh, C.; Toth, C. L.; Cougnoux, A.; Burkert, K. R.; Bianconi, S. E.; Wassif, C. A.; Porter, F. D., Altered cerebrospinal fluid proteins in Smith–Lemli–Opitz syndrome patients. American Journal of Medical Genetics Part A 2016, 170 (8), 2060-2068. doi: 10.1002/ajmg.a.37720

12. Nicoli, E.-R.; Al Eisa, N.; Cluzeau, C. V. M.; Wassif, C. A.; Gray, J.; Burkert, K. R.; Smith, D. A.; Morris, L.; Cologna, S. M.; Peer, C. J.; Sissung, T. M.; Uscatu, C.-D.; Figg, W. D.; Pavan, W. J.; Vite, C. H.; Porter, F. D.; Platt, F. M., Defective Cytochrome P450-Catalysed Drug Metabolism in Niemann-Pick Type C Disease. PLOS ONE 2016, 11 (3), e0152007. doi: 10.1371/journal.pone.0152007

Prior to 2015

11. S.M. Cologna, C.A. Crutchfield, B.C. Searle , P.S. Blank, C. L. Toth, A. M. Ely, J.A. Picache, P.S. Backlund, C.A. Wassif, F.D. Porter,  A.L Yergey, ” An Efficient Approach to Evaluate Reporter Ion Behavior from MALDI-MS/MS Data for Quantification Studies using Isobaric Tags,” Journal of Proteome Research, 2015, 14 (10), pp 4169–4178. DOI: 10.1021/acs.jproteome.5b00254

10. M.L.  Rauschecker, S.M. Cologna, N. Nilobul, R.D. Shamburek, P.S. Backlund, A.L. Yergey, E. Kebebew, J.E. Balow, C.A. Stratakis, S. Abraham, “LECT2-associated Adrenal Amyloidosis,” AACE Clinical Case Rep., 1(1), e59-67, 2015DOI: 10.4158/EP13443.CR

9. S.M. Cologna*, C.V.M. Cluzeau*, N.M. Yanjanin, P.S. Blank, M.K. Dail, S. Siebel, C.L. Toth, C.A. Wassif, A.P.  Lieberman, F.D. Porter. “Human and mouse neuroinflammation markers in Niemann-Pick disease, type C1,” Journal of Inherited Metabolic Disease, 37 (1), 83-92, 2014. (*authors contributed equally).  DOI : 10.1007/s10545-013-9610-6

8. S.M. Cologna,  X-S. Jiang, P.S. Backlund, C.V.M. Cluzeau, M.K. Dail, N.M. Yanjanin, S. Siebel, C. L. Toth, H-s. Jun, C.A. Wassif, A.L. Yergey, F.D. Porter, “Quantitative Proteomic Analysis of Niemann-Pick Disease, type C1 Cerebellum Identifies Protein Biomarkers and Provides Pathological Insight,” PLoS One, 7(10):e47845, 2012. DOI: 10.1371/journal.pone.0047845

7. S.M. Cologna, W.K. Russell, G. Vigh, and D.H. Russell “Studies of Histidine as a Suitable Isoelectric Buffer for Tryptic Digestion and Isoelectric Trapping Fractionation followed by Capillary Electrophoresis – Mass Spectrometry for Proteomic Analysis,” Analytical Chemistry, 83(21), 8108-8114, 2011DOI : 10.1021/ac201237r

6. B.W. Newton*, S.M. Cologna*, C. Moya, D.H. Russell, W. K. Russell and A. Jayaraman “Proteomic Analysis of 3T3-L1 Adipocyte Mitochondria During Differentiation, Maturation and Hypertrophic Enlargement,” Journal of Proteome Research, 10(10), 4692-4702, 2011. (*authors contributed equally).  DOI : 10.1016/j.tem.2012.06.004

5. J.J. Gill, E.J. Summer, W.K. Russell, S.M. Cologna, T. Carlile, A. Fuller, K. Kitsopoulos, L. Mebane, B. Parkinson, D. Sullivan, L. Carmody, C.F. Gonzalez, J.J. LiPuma, and R. Young “Genome and characterization of phages Bcep22 and BcepIL02, founders of a novel phage type in Burkholderia cenocepacia,” Journal of Bacteriology, 193(19), 5300-5313, 2011DOI : 10.1128/JB.05287-11

4. P-J. Pai*, S.M. Cologna*, W.K. Russell, G. Vigh and D.H. Russell, “Efficient Electrophoretic Method to Remove Neutral Additives from Protein Solutions Followed by Mass Spectrometry Analysis,” Analytical Chemistry, 83(7), 2814-2818, 2011 (*authors contributed equally). DOI : 10.1021/ac1029743

3. S.M. Cologna, W.K. Russell, P.J. Lim, G. Vigh, and D.H. Russell “Combining Isoelectric Point Fractionation, Liquid Chromatography and Mass Spectrometry to Increase Peptide Detection and Protein Identification,” Journal of the American Society for Mass Spectrometry, 21(9), 16121619, 2010. DOI : 10.1016/j.jasms.2010.04.010

2. C.Becker, F.A.Fernandez-Lima, K.J. Gillig, W.K. Russell, S.M. Cologna and D.H. Russell “A Novel Approach to Collision-Induced Dissociation (CID) for Ion-Mobility Mass Spectrometry Experiments,”Journal of the American Society for Mass Spectrometry, 20, 907-914, 2009.    DOI : 10.1016/j.jasms.2008.11.026

1. K.M. Miranda, T. Katori, C.L. Torres de Holding, L. Thomas, L.A. Ridnour, W.J. McLendon, S.M. Cologna, A.S. Dutton, H.C. Champion, D. Mancardi, C.G. Tochetti, J.E. Saavedra, L.K. Keefer, K.N. Houk, J.M. Fukuto, D.A. Kass, N. Paolocci, and D.A. Wink, “Comparison of the NO and HNO donating properties of diazeniumdiolates:  primary amine adducts release HNO in vivo,” Journal of Medicinal Chemistry, 48(26), 8220-8228, 2005.   DOI : 10.1021/jm050151i