Publications

“Akap5 links synaptic dysfunction to neuroinflammatory signaling in a mouse model of infantile neuronal ceroid lipofuscinosis.” Koster, Kevin P., et al., Frontiers in Synaptic Neuroscience, 2024. DOI: https://doi.org/10.3389/fnsyn.2024.1384625

“Endogenous Protein–Protein Interaction Network of the NPC Cholesterol Transporter 1 in the Cerebral Cortex.” Javanshad, Roshan, et al., Journal of Proteome Research, 2024. DOI: https://doi.org/10.1021/acs.jproteome.3c00788

“Proteomics insights into fragile X syndrome: Unraveling molecular mechanisms and therapeutic avenues.” Abbasi, Diana A., et al., Neurobiology of Disease, 2024. DOI: https://doi.org/10.1016/j.nbd.2024.106486

“Follicular fluid aids in cell adhesion, spreading and shows an age-dependent effect on DNA damage in fallopian tube epithelial cells.” Salvi, Amrita, et al., Heliyon, 2024. DOI: https://doi.org/10.1016/j.heliyon.2024.e27336

“Temporal alterations in white matter in an App knock-in mouse model of Alzheimer’s disease.” Morrissey, Zachery D., et al., eneuro, 2024. DOI: https://doi.org/10.1523/ENEURO.0496-23.2024

“In Vivo Simvastatin and Brain Radiation in a Model of HER2+ Inflammatory Breast Cancer Brain Metastasis.” Kumar, Swaminathan, et al., bioRchiv, 2024. DOI: https://doi.org/10.1101/2024.05.25.595905

“Discovery of a Small-Molecule Modulator of the Autophagy-Lysosome Pathway That Targets Lamin A/C and LAMP1, Induces Autophagic Flux, and Affects Lysosome Positioning in Neurons.” Hippman, Ryan S., et al., ACS Chemical Neuroscience, 2023. DOI: https://doi.org/10.1021/acschemneuro.3c00573

“Comparative Hippocampal Proteome and Phosphoproteome in a Niemann–Pick, Type C1 Mouse Model Reveal Insights into Disease Mechanisms.” Nguyen, Thu Ta, et al., Journal of Proteome Research, 2023. DOI: https://doi.org/10.1021/acs.jproteome.3c00375

“CD36 maintains lipid homeostasis via selective uptake of monounsaturated fatty acids during matrix detachment and tumor progression.” Terry, Alexander R., et al., Cell Metabolism, 2023. DOI: 10.1016/j.cmet.2023.09.012

“α-Synuclein-dependent increases in PIP5K1γ drive inositol signaling to promote neurotoxicity.” Horvath, Jonathan D., et al., Cell Reports, 2023. DOI: 10.1016/j.celrep.2023.113244

“Caveolin-1 Autonomously Regulates Hippocampal Neurogenesis Via Mitochondrial Dynamics.” Stephen, Terilyn K L, et al., bioRxiv, 2023. DOI: 10.1101/2023.09.23.558792

“Relative quantification of progressive changes in healthy and dysferlin-deficient mouse skeletal muscle proteomes.” Golding, Adriana E, et al., Muscle & Nerve, 2023. DOI: 10.1002/mus.27975

“Elevated cerebrospinal fluid ubiquitin C-terminal hydrolase-L1 levels correlate with phenotypic severity and therapeutic response in Niemann-Pick disease, type C1.” Cawley, Niamh X., et al., Molecular Genetics and Metabolism, 2023. https://doi.org/10.1016/j.ymgme.2023.107656

“Reduced endothelial caveolin-1 underlies deficits in brain insulin signalling in type 2 diabetes.” Shetti, Aashutosh U, et al., Brain, 2023. https://doi.org/10.1093/brain/awad028

“An integrated approach to protein discovery and detection from complex biofluids.” Luu, Gordon T., et al., Molecular and Cellular Proteomics, 2023. https://doi.org/10.1016/j.mcpro.2023.100590

“3D Quantification of Elemental Gradients within Heterostructured Particles of Battery Cathodes.” Allen, Eva, et al., ACS Energy Letters, 2023.
DOI: 10.1021/acsenergylett.2c02619

“A differential proteomics study of cerebrospinal fluid from individuals with Niemann-Pick disease, Type C1.” Li, Wenping, et al., Proteomics, 2023. https://doi.org/10.1002/pmic.202200378

“SMART: A data reporting standard for mass spectrometry imaging.” Xi, Ying, et al., Journal of Mass Spectrometry, 2023. https://doi.org/10.1002/jms.4904

“PAX8 modulates the tumor microenvironment of high grade serous ovarian cancer through changes in the secretome.” Salvi, Amrita, et al., Neoplasia, 2023. https://doi.org/10.1016/j.neo.2022.100866

“Identification of cerebral spinal fluid protein biomarkers in Niemann-Pick disease, type C1.” Campbell, Kiersten, et al., Biomarker Research, 2023. https://doi.org/10.1186/s40364-023-00448-x

“Alterations in Cholesterol and Phosphoinositides Levels in the Intracellular Cholesterol Trafficking Disorder NPC.” Cologna, Stephanie M., et al., Advances in Experimental Medicine and Biology, 2023. https://doi.org/10.1007/978-3-031-21547-6_5

“Species-specific differences in NPC1 protein trafficking govern therapeutic response in Niemann-Pick type C disease.” Shultz, Mark L., et al., JCI Insight, 2022. https://doi.org/10.1172%2Fjci.insight.160308

“Fallopian tube secreted protein affects ovarian metabolites in high grade serous ovarian cancer.”  Bergsten, Tova M., et al., Frontiers in Cell and Developmental Biology, 2022. https://doi.org/10.3389/fcell.2022.1042734

“Steroid hormones of the octopus self-destruct system.” Wang, Z. Yan, et al., Current Biology, 2022. https://doi.org/10.1016/j.cub.2022.04.043

“Mass spectrometry-based proteomics in neurodegenerative lysosomal storage disorders.” Li, Wenping, Cologna, Stephanie, Molecular Omics, 2022. https://doi.org/10.1039/D2MO00004K

“Non-Cytokine Protein Profile of the Mesenchymal Stem Cell Secretome That Regulates the Androgen Production Pathway.” Park, Hang-Soo, et al., International Journal of Medical Sciences, 2022. https://doi.org/10.3390/ijms23094633

“Lipidomic analysis identifies age-disease-related changes and potential new biomarkers in brain-derived extracellular vesicles from metachromatic leukodystrophy mice.” Pergande, Melissa R., et al., Lipids in Health and Disease, 2022. https://doi.org/10.1186/s12944-022-01644-8

“Characterization of the Cerebrospinal Fluid Proteome in Patients with Fragile X-Associated Tremor/Ataxia Syndrome.” Abbasi, Diana A., et al., The Cerebellum, 2022. https://doi.org/10.1007/s12311-021-01262-7

“PHY34 inhibits autophagy through V-ATPase V0A2 subunit inhibition and CAS/CSE1L nuclear cargo trafficking in high grade serous ovarian cancer.” Salvi, Amrita, et al., Cell Death and Disease, 2022. https://doi.org/10.1038/s41419-021-04495-w

“Histatin‐1 is an endogenous ligand of the sigma‐2 receptor.” Son, Kyung-No, et al., The FEBS Journal, 2022. 10.1111/febs.16108

“PPARα and PPARγ signaling is enhanced in the brain of the naked mole-rat, a mammal that shows intrinsic neuroprotection from oxygen deprivation.” Pergande, Melissa R., et al., Journal of Proteome Research, 2021. https://doi.org/10.1021/acs.jproteome.1c00131

“Waning efficacy in a long-term AAV-mediated gene therapy study in the murine model of Krabbe disease.” Heller, Gregory J., et al., Molecular Therapy, 2021. https://doi.org/10.1016/j.ymthe.2021.01.026

“Visualizing cholesterol in the brain by on-tissue derivatization and quantitative mass spectrometry imaging.” Angelini, Roberto, et al., Analytical Chemistry, 2021. https://doi.org/10.1021/acs.analchem.0c05399

“Synaptic function and dysfunction in lysosomal storage diseases.” Rebiai, Rima, et al., Frontiers in Cellular Neuroscience, 2021. https://doi.org/10.3389/fncel.2021.619777

“Mass spectrometry-based lipid analysis and imaging.” Pathmasiri, Koralege C., et al., Current Topics in Membranes, 2021. https://doi.org/10.1016/bs.ctm.2021.10.005

“Deregulation of signalling in genetic conditions affecting the lysosomal metabolism of cholesterol and galactosyl-sphingolipids.” Gowrishankar, S., et al., Neurobiology of Disease, 2020. https://doi.org/10.1016/j.nbd.2020.105142

“Cholesterol-rich naked mole-rat brain lipid membranes are susceptible to amyloid beta-induced damage in vitro.” Frankel, Daniel, et al.,  Aging, 2020. 10.18632/aging.202138

“Taurine Is Covalently Incorporated into Alpha-Tubulin.” Olson, Matthew, et al., Journal of Proteome Research, 2020. https://dx.doi.org/10.1021/acs.jproteome.0c00147?ref=pdf

“Mass spectrometry imaging and LC/MS reveal decreased cerebellar phosphoinositides in Niemann-Pick type C1-null mice[S].” Pathmasiri, Koralege C., et al., Journal of Lipid Research, 2020. https://doi.org/10.1194/jlr.RA119000606

“Activated mesenchymal stem cells induce recovery following stroke via regulation of inflammation and oligodendrogenesis.” Tobin, Matthew, et al., Journal of the American Heart Association, 2020. DOI: 10.1161/JAHA.119.013583

“Considerations for mass spectrometry-based multi-omic analysis of clinical samples.” Teclemariam, Esei T., et al, Expert Review of Proteomics, 2020. https://doi.org/10.1080/14789450.2020.1724540

“A calcium message for Niemann-Pick type C.” Cologna, Stephanie, The Journal of Cell Biology, 2019.  https://doi.org/10.1083%2Fjcb.201911021

“Lipidomic analysis reveals altered fatty acid metabolism in the liver of the symptomatic Niemann–Pick, Type C1 mouse model.” Pergande, Melissa R., et al., Proteomics, 2019. https://doi.org/10.1002/pmic.201800285

“Mass spectrometry imaging reveals ganglioside and ceramide localization patterns during cerebellar degeneration in the Npc1−/− mouse model.” Tobias, Fernando, et al., 2019. https://doi.org/10.1007/s00216-019-01989-7

“Proteomic analysis reveals a role for PAX8 in peritoneal colonization of high grade serous ovarian cancer that can be targeted with micelle encapsulated thiostrepton.” Hardy, Laura R., et al., Oncogene, 2019. https://doi.org/10.1038/s41388-019-0842-2

“Investigating phosphorylation patterns of the ion channel TRPM7 using multiple extraction and enrichment techniques reveals new phosphosites.” Nguyen, Thu TA, et al., Journal of the American Society for Mass Spectrometry, 2019. https://doi.org/10.1007/s13361-019-02223-5

“Standard-flow LC and thermal focusing ESI elucidates altered liver proteins in late stage Niemann–Pick, type C1 disease.” Pergande, Melissa R., et al., Bioanalysis, 2019. DOI: 10.4155/bio-2018-0232

“Extracellular and intracellular sphingosine‐1‐phosphate distinctly regulates exocytosis in chromaffin cells.” Jiang, Zhong-Jiao, et al., Journal of Neurochemistry, 2019. DOI: 10.1111/jnc.14703

“Quantitative, Label‐Free Proteomics in the Symptomatic Niemann–Pick, Type C1 Mouse Model Using Standard Flow Liquid Chromatography and Thermal Focusing Electrospray Ionization.” Pergande, Melissa R., et al., Proteomics, 2019. DOI: 10.1002/pmic.201800432

“Exposure to microwave irradiation at constant culture temperature slows the growth of Escherichia coli DE3 cells, leading to modified proteomic profiles.” Mazinani, Sina Atrin, et al., RSC Advances, 2019. https://doi.org/10.1039/C9RA00617F

“Changes to the human serum proteome in response to high intensity interval exercise: A sequential top-down proteomic analysis.” Kurgan, Nigel, et al., Frontiers in Physiology, 2019. https://doi.org/10.3389/fphys.2019.00362

“Differential proteomics reveals miR-155 as a novel indicator of liver and spleen pathology in the symptomatic Niemann-Pick Disease, type C1 mouse model.” Pergande, Melissa R., et al, Molecules, 2019. http://dx.doi.org/10.3390/molecules24050994

“Insights into the molecular mechanisms of cholesterol binding to the NPC1 and NPC2 proteins.” Cologna, Stephanie M., Direct Mechanisms in Cholesterol Modulation of Protein Function. 2019. DOI: 10.1007/978-3-030-14265-0_8

“Mass spectrometry imaging of cholesterol.” Cologna, Stephanie M., Direct Modulation of Protein Function, 2019.

“Mass spectrometry imaging of lipids: untargeted consensus spectra reveal spatial distributions in Niemann-Pick disease type C1.” Tobias, Fernando, et al., Journal of Lipid Research, 2018. https://doi.org/10.1194/jlr.D086090

“Cyclodextrin and malto-dextrose collision cross sections determined in a drift tube ion mobility mass spectrometer using nitrogen bath gas.” Klein, Christian, et al., Analyst, 2018. https://doi.org/10.1039/C8AN00646F

“Characterization of hydroxypropyl-beta-cyclodextrins used in the treatment of Niemann-Pick Disease type C1.” Yergey, Alfred L., PLOS ONE, 2017. https://doi.org/10.1371/journal.pone.0175478

“Isoelectric point separations of peptides and proteins.” Pergande, Melissa R., Cologna, Stephanie M., Proteomes, 2017.

“ProteinProcessor: A probabilistic analysis using mass accuracy and the MS spectrum.” Epstein, Jonathan A., et al., Proteomics, 2016. DOI: 10.1002/pmic.201600137

“Altered cerebrospinal fluid proteins in Smith-Lemli-Opitz syndrome patients.” Cologna, Stephanie M., et al.,  American Journal of Medical Genetics, 2016. DOI: 10.1002/ajmg.a.37720

“Defective Cytochrome P450-Catalysed Drug Metabolism in Niemann-Pick Type C Disease.” Nicoli, Elena-Raluca, et al., PLOS ONE, 2016. DOI: 10.1371/journal.pone.0152007

“An Efficient Approach to Evaluate Reporter Ion Behavior from MALDI-MS/MS Data for Quantification Studies Using Isobaric Tags.” Cologna, Stephanie M., et al.,  Journal of Proteome Research, 2015. DOI: 10.1021/acs.jproteome.5b00254